|
|
| Carneiro,Jaqueline; Döll-Boscardin,Patrícia Mathias; Fiorin,Bárbara Celânia; Nadal,Jessica Mendes; Farago,Paulo Vitor; Paula,Josiane Padilha de. |
| ABSTRACT Skin aging causes changes such as wrinkles and flaccidity leading to a large demand for aesthetic procedures, including dermal filling. A key agent in dermal filling is hyaluronic acid (HA), which is a naturally occurring glycosaminoglycan. However, it is a hydrophilic macromolecule that experiences great difficulty in crossing the skin barrier causing most commercial formulations containing it to be injectable, which in turn brings risks since they involve an invasive technique. In that sense, the aim of this study was to develop and characterize nanoparticles obtained from ionic interaction between HA and lysine (Lys) for use as a potential agent of dermal filling for topical application, increasing and improving its applicability and safety. To... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nanotechnology; Skin aging/non-invasive method; Skin aging/treatment/study.. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000400645 |
| |
